Human HE4 Protein (Glu 31-Phe 124) [His] [Avi] (VAng-1709Lsx)
Biotinylated Human HE4, His tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: Q14508-1)
Target
Human Epididymis Protein 4
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
Human Epididymis Protein 4 is a protein that is produced by most, but not all, epithelial ovarian cancer cells. This makes the test useful as a tumor marker in specific circumstances. The HE4 test measures the amount of human epididymis protein 4 in the blood. Significantly elevated concentrations of HE4 are frequently present in the blood of a woman who has epithelial ovarian cancer. When HE4 is increased, the HE4 test may be used to monitor the effectiveness of treatment and/or for recurrence of the cancer. However, HE4 is not recommended as a screening test for asymptomatic women because it is non-specific. Small quantities of HE4 are produced by normal tissues throughout the body and mild elevations may be seen with a variety of non-cancerous conditions. HE4 is not recommended as a screening test for asymptomatic women because it is non-specific. Small quantities of HE4 are produced by normal tissues throughout the body and mild elevations may be seen with a variety of non-cancerous conditions.
Alternative Names
HE4, WAP5, WFDC2, EDDM4
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