Human Leptin R Protein (Phe 22-Asp 839) [Fc] (VAng-1883Lsx)
Human LDLR protein, human IgG1 Fc tag, expressed in human 293 cells. (Uniprot ID: NP_002294.2)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, Ph 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
LEPR (Leptin Receptor) belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis.
Alternative Names
LEPR, CD295, DKFZp686B1731, OBR, Leptin receptor
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