Pepsinogen I Antigen (VAng-Cr3887)
Pepsinogen I Antigen, Host/Source: Human Stomach. The purity is ≥90% by SDS-PAGE.
Datasheet
Specifications
Source
Human Stomach
Target
Pepsinogen I
Type
Tumor Antigens
Applications
ELISA, WB, Controls.
Formulation
Lyophilized.
Purity
≥ 90% pure by SDS-PAGE.
Storage
Store at -20°C.
Antigen Information
Introduction
Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kDa. Pepsinogen I is synthesized at gastric chief cells and mucous neck cells, while Pepsinogen II is produced not only by gastric chief cells, mucous neck cells, but also by clear mucous cells of antrum. The clinical applications of measuring pepsinogen are of useful aid in diagnosing severe
atrophic gastritis and stomach cancer. Low serum pepsinogen I levels were found in individuals with gastric cancer, with a threefold higher incidence. Other studies have concluded that low serum.
atrophic gastritis and stomach cancer. Low serum pepsinogen I levels were found in individuals with gastric cancer, with a threefold higher incidence. Other studies have concluded that low serum.
Alternative Names
PGI
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