Recombinant Cynomolgus B7-2 Protein (aa 19-240) [Fc] (VAng-3473Lsx)
Recombinant Cynomolgus B7-2 (CD86) Protein, expressed in HEK293 Cells. (Uniprot ID: G7NXR4)
Datasheet
Specifications
Source
HEK293 Cells
Target
B7-2
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
B7-2 is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells. Its gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Alternative Names
CD86; B7.2; B70; CD28LG2; LAB72; CD86 molecule
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
