Human FGF basic Protein (Pro 143-Ser 288) (VAng-1554Lsx)

Human FGF basic is expressed in E. coli. (Uniprot ID: NP_001997)

Datasheet

Specifications

Source

E. coli

Target

FGF basic

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 98% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

FGF2 (Fibroblast Growth Factor 2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Alternative Names

FGF2, BFGF, FGFB, FGF basic, HBGF-2