Recombinant FOLH1 Protein (Lys44-Ala750) [TwinStrep] (VAng-Cr3807)
Recombinant FOLH1 Protein (Lys44-Ala750) fused with a TwinStrep tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 100 kDa. (Uniprot ID: Q04609)
Datasheet
Specifications
Source
Mammalian cells
Target
FOLH1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
FOLH1 is an enzyme that in humans is encoded by FOLH1 gene. Human GCP2 contains 750 amino acids and weighs approximately 84 kDa. GCP2 is a zinc metalloenzyme that resides in membranes. Most of the enzyme resides in the extracellular space. GCP2 is a class 2 membrane glycoprotein. It catalyzes the hydrolysis of N-acetylaspartylglutamate (NAAG) to glutamate and N-acetylaspartate (NAA) according to the reaction scheme to the right. Neuroscientists primarily use the term NAALADase in their studies, while those studying folate metabolism use folate hydrolase, and those studying prostate cancer or oncology, PSMA. All of which refer to the same protein glutamate carboxypeptidase 2.
Alternative Names
FGCP; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSM; PSMA; mGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1
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