Recombinant Galectin-9 Protein (Met1-Gln148) [His] (VAng-Cr3857)

Recombinant Galectin-9 Protein (Met1-Gln148) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 16.39 kDa. (Uniprot ID: O00182)

Datasheet

Specifications

Source

Mammalian cells

Target

Galectin-9

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

Galectin-9 is firstly isolated from mouse embryonic kidney as a 36 kDa beta-galactoside lectin protein. The protein has N- and C- terminal carbohydrate-binding domains connected by a link peptide. Multiple alternatively spliced transcript variants have been found. Galectin-9 is one of the most studied ligand for HAVCR2 (TIM-3) and is expressed on various tumor cells. However, it can also interact with other proteins (CLEC7A, CD137, CD40). The expression of galectin-9 has been detected on various hematological malignancies, such as CLL, MDS, Hodgkin and Non-Hodgkin lymphomas, AML or solid tumors, such as lung cancer, breast cancer, and hepatocellular carcinoma.

Alternative Names

LGALS9; HUAT; LGALS9A