Recombinant HPV-18 L1 Protein (Hansenula polymorpha) (VAng-0555Lsx)

HPV type 18 L1 Protein, recombinant protein from Hansenula polymorpha. 2.22 mg/mL.

Specifications
Source
Hansenula polymorpha
Target
Human Papillomavirus
Type
Viral Antigens
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Formulation
20 mM Potassium Dihydrogen Phosphate (KH₂PO₄), pH 7.2 containing 500 mM Sodium Chloride, 1.7 mM
EDTA, 0.01% Tween-80 and 1 mM 2-Mercaptoethanol.
Purity
> 90 % pure by SDS-PAGE.
Storage
Store at -20°C.
Antigen Information
Introduction
HPVs are non-enveloped, double-stranded DNA viruses, which are tropic for mucosal tissues. The genome consists of three functionally divided regions: (a) a noncoding regulatory region; (b) an early proteins region, which encodes for six early proteins (E1, E2, E4-E7); and (c) a late region, which encodes for the viral capsid proteins L1 and L2. HPVs infect basal epithelial (skin or mucosal) cells. More than 200 HPV genotypes have been identified. Oncogenic genotypes include HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 66. Most HPV infections cause no symptoms and resolve spontaneously. In some people, an HPV infection persists and results in warts or precancerous lesions. The precancerous lesions increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, or throat. Nearly all cervical cancer is due to HPV with two types, HPV16 and HPV18, accounting for 70 % of cases.
Alternative Names
HPV18 major capsid protein L1; Human Papilloma Virus Type 18 Major Capsid Protein L1; Human papillomavirus type 18 L1; Human papilloma virus type 18 major capsid protein L1; Papillomaviridae
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All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.


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All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.

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