Recombinant HPV-18 Protein [GST] (VAng-Lsx0276)

HPV type 18 [GST], recombinant protein from E. coli.

Specifications
Source
Human
Target
Human Papillomavirus
Type
Viral Antigens
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Formulation
1xPBS, 20mM arginine and 0.02 % sodium azide as preservative.
Purity
> 95 % pure by 12 % SDS-PAGE.
Storage
Store at 2 °C to 8 °C short term, -20 °C long term.
Antigen Information
Introduction
HPVs are non-enveloped, double-stranded DNA viruses, which are tropic for mucosal tissues. The genome consists of three functionally divided regions: (a) a noncoding regulatory region; (b) an early proteins region, which encodes for six early proteins (E1, E2, E4-E7); and (c) a late region, which encodes for the viral capsid proteins L1 and L2. HPVs infect basal epithelial (skin or mucosal) cells. More than 200 HPV genotypes have been identified. Oncogenic genotypes include HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 66. Most HPV infections cause no symptoms and resolve spontaneously. In some people, an HPV infection persists and results in warts or precancerous lesions. The precancerous lesions increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, or throat. Nearly all cervical cancer is due to HPV with two types, HPV16 and HPV18, accounting for 70 % of cases.
Alternative Names
HPV 18; Human papillomavirus 18
Related Product

For lab research use only, not for diagnostics, therapeutic or any in vivo human use.

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