Recombinant MET Protein (Met1-Thr932) [His] (VAng-Cr3800)
Recombinant MET Protein (Met1-Thr932) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 45-85 kDa. (Uniprot ID: P08581)
Datasheet
Specifications
Source
Mammalian cells
Target
MET
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
MET is a protein that in humans is encoded by MET gene. The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. MET is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its splicing isoform (NK1, NK2) are the only known ligands of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF/SF is restricted to cells of mesenchymal origin.
Alternative Names
MET proto-oncogene; receptor tyrosine kinase; AUTS9; HGFR; RCCP2; c-Met; DFNB97; OSFD
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