Recombinant TNF Protein (Val77-Leu233) [His] (VAng-Cr3754)
Recombinant TNF Protein (Val77-Leu233) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 17.32 kDa. (Uniprot ID: P01375)
Datasheet
Specifications
Source
Mammalian cells
Target
TNF
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
TNF is a protein superfamily member of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and regulate diverse cell functions, including regulation of immune response and inflammation, but also proliferation, differentation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. An occurrence of orthologs in invertebrates hints at ancient origin of this superfamily in evolution.
Alternative Names
TNFA; TNFSF2
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