3'3'-cGAMP (VAdv-Ly0020)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0020 |
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3'3'-cGAMP, (cyclic [G(3', 5')pA(3', 5')p]), a STING agonist vaccine adjuvant.
Datasheet
Specifications
Type
PRRs Agonist
Formula
C20H22N10O13P2▪2Na
Molecular Weight
718.38
Specificity
Th1/Th2 response
Product Form
White solid
Percentage
≥ 95% by LC/MS
Endotoxin
Lower than 5 EU/mg.
Storage
Store at -20°C.
Shelf Life
1 year.
Adjuvant Information
Introduction
3'3'-cGAMP, also known as cyclic [G(3', 5')pA(3', 5')p], is a bacterial-derived cyclic dinucleotide that functions as a crucial second messenger. Within bacteria, it mediates processes like chemotaxis and colonization. Notably, 3'3'-cGAMP possesses the ability to bind STING, triggering a signaling cascade involving TBK1 (TANK-binding kinase 1) and IRF3 (IFN regulatory transcription factor 3), ultimately leading to the production of IFN-β.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
