Cancer Antigen CA-125 Antigen (Human Adenocarcinoma) (VAng-Wyb8642)
CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.
Source
Human Adenocarcinoma.
Applications
Immunoassays.
Formulation
20 mM Tris-HCl, pH 7.5 containing 0.1% Sodium Chloride.
Purity
> 50% pure by SDS-PAGE.
Introduction
CA-125 is a protein that in humans is encoded by CA-125 gene. It is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, or other conditions that are benign. It is a membrane associated mucin that possesses a single transmembrane domain. A unique property of MUC16 is its large size. CA-125 is more than twice as long as MUC1 and MUC4 and contains about 22,000 amino acids, making it the largest membrane-associated mucin.
Alternative Names
CA 125; MUC16; CA125; mucin 16
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