Recombinant CA-125 Protein (Gly 12660-Met 12923) [Fc] [Avi] (VAng-1153Lsx)
Biotinylated Human CA-125 (MUC16), Fc tag, Avi tag, is expressed in HEK 293 cells. (Uniprot ID: Q8WXI7-1)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
CA-125 is a protein that in humans is encoded by CA-125 gene. It is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, or other conditions that are benign. It is a membrane associated mucin that possesses a single transmembrane domain. A unique property of MUC16 is its large size. CA-125 is more than twice as long as MUC1 and MUC4 and contains about 22,000 amino acids, making it the largest membrane-associated mucin.
Alternative Names
CA125, CA-125, CA125MUC-16, FLJ14303, MUC16, mucin 16, mucin-16
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