Cancer Antigen CEA Antigen (Human Metastatic Liver) (VAng-Wyb8645)
Carcinoembryonic Antigen, Antigen Grade, Cancer antigen from Human Metastatic Liver, 5.5 mg/mL.
Source
Human Metastatic Liver.
Applications
Immunogen for antisera production, tracer for iodination and standard for Immunoassay.
Formulation
0.1 M Phosphate Buffered Saline, pH 7.4 containing 2.0% Methyl-Mannoside.
Introduction
CEA is a member of the carcinoembryonic antigen family. It plays a role in cell adhesion, intracellular signaling and tumor progression. It mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules. The protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. Its gene is present in a CEA family on chromosome 19. Alternative splicing results in multiple transcript variants.
Alternative Names
CEACAM5
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