Recombinant 4-1BB Ligand / TNFSF9 Protein (Ala 50-Glu 254) [Fc] [Avi] (VAng-0694Lsx)
Biotinylated Human 4-1BB ligand, human IgG1 Fc tag, Avi tag, was expressed in HEK 293 cells, with a molecular weight of 50.2 kDa. (Uniprot ID: P41273-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
4-1BBL
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
4-1BBL is found on APCs (antigen presenting cells) and binds to 4-1BB. Therapies utilizing the 4-1BB:4-1BBL signaling pathway have been shown to have antitumor effects in a number of model systems. It is a membrane bound member of the TNF superfamily that is expressed on activated B-cells; macrophage; and dendritic cells. The ligand is specific for the 4-1BB receptor and may play a role in inducing the proliferation of activated peripheral blood T-cells.
Alternative Names
4-1BB ligand; TNFSF9; CD137L
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
