Recombinant 4-1BBL Protein (Ala50-Glu254) [His] (VAng-Cr3830)
Recombinant 4-1BBL Protein (Ala50-Glu254) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 22.64 kDa. (Uniprot ID: P41273)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
4-1BBL is found on APCs (antigen presenting cells) and binds to 4-1BB. Therapies utilizing the 4-1BB:4-1BBL signaling pathway have been shown to have antitumor effects in a number of model systems. It is a membrane bound member of the TNF superfamily that is expressed on activated B-cells; macrophage; and dendritic cells. The ligand is specific for the 4-1BB receptor and may play a role in inducing the proliferation of activated peripheral blood T-cells.
Alternative Names
4-1BB ligand
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