Recombinant CA-50 Protein (VAng-Wyb8636)
CA-50, Calibrator Grade, recombinant protein from Cell Culture, 40681 U/mL.
Datasheet
Specifications
Source
Cell Culture.
Target
CA-50
Type
Tumor Antigens
Applications
Immunoassays.
Formulation
Phosphate Buffered Saline, pH 7.4 ± 0.1.
Storage
Store at 2-8°C for short time, aliquot and store at -20°C for long term.
Antigen Information
Introduction
CA-50, a novel cancer-associated carbohydrate marker, is detected by the C 50 antibody that has been obtained by immunization of mice with a human colorectal adenocarcinoma cell line. This antibody that defines CA 50 reacts with both the afucosyl form of sialylated Lewis(a) carbohydrate moiety and sialylated Lewis(a) moiety which is also the antigenic epitope in the CA 19-9 assay. CA 50 is not organ-specific and its elevated levels in serum can be observed in a variety of malignancies, especially gastrointestinal cancers. In contrast to CA 19-9, high CA 50 levels can also be seen in malignant tumors outside the digestive tract. The expectation, that CA 50 might be positive in the Lewis negative patients who cannot synthesize CA 19-9, is supported by the histoimmunologic study.
Alternative Names
CA50
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
