Recombinant CD160 Protein (Met1-Leu158) [His] (VAng-Cr3840)
Recombinant CD160 Protein (Met1-Leu158) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 25 kDa. (Uniprot ID: O95971)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
CD160 is a 27 kDa glycoprotein which is initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine.
Alternative Names
BY55; NK1; NK28; CD160 molecule
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