Recombinant Mouse CD160 Protein (aa 33-171) (E. coli) [His] [T7] (VAng-4452Lsx)

CD160

Tumor Antigens

SDS-PAGE; WB; ELISA.

PBS, pH 7.4.

> 90% pure by SDS-PAGE.

Store at -20°C to -80°C.

CD160 is a 27 kDa glycoprotein which is initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine.

CD160, BY55, NK1, NK28