Recombinant CD38 Protein (Leu 44-Ile 301) (VAng-1280Lsx)
Cynomolgus CD38 is expressed in HEK 293 cells. (Uniprot ID: Q5VAN0-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD38
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM MES, 100 mM NaCl, pH 6.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD38 is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose in addition to synthesis of NAADP from NADP+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism.
Alternative Names
CD38, T10, cADPr hydrolase 1
Related Product
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