Recombinant CD38 Protein (Val 43-Ile 300) [His] (VAng-1286Lsx)

Human CD38, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001766.2)

Datasheet

Specifications

Source

HEK293 Cells.

Target

CD38

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

50 mM MES, 100 mM NaCl, pH 6.5.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CD38 is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose in addition to synthesis of NAADP from NADP+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism.

Alternative Names

CD38, T10, cADPr hydrolase 1