Recombinant HPV-16 L1 Protein (S. cerevisiae) (VAng-Lsx0270)

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VAng-Lsx0270

HPV type 16 L1 Protein, recombinant protein from S. cerevisiae.

Specifications
Source
Human
Target
Human Papillomavirus
Type
Viral Antigens
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Formulation
0.05M Phosphate, pH 7.2 containing 0.2M Sodium chloride and 0.01 % Tween-80.
Purity
> 90 % pure by SDS-PAGE.
Storage
Store at 2 °C to 8 °C short term, -20 °C long term.
Antigen Information
Introduction
HPVs are non-enveloped, double-stranded DNA viruses, which are tropic for mucosal tissues. The genome consists of three functionally divided regions: (a) a noncoding regulatory region; (b) an early proteins region, which encodes for six early proteins (E1, E2, E4-E7); and (c) a late region, which encodes for the viral capsid proteins L1 and L2. HPVs infect basal epithelial (skin or mucosal) cells. More than 200 HPV genotypes have been identified. Oncogenic genotypes include HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 66. Most HPV infections cause no symptoms and resolve spontaneously. In some people, an HPV infection persists and results in warts or precancerous lesions. The precancerous lesions increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, or throat. Nearly all cervical cancer is due to HPV with two types, HPV16 and HPV18, accounting for 70 % of cases.
Alternative Names
HPV-16; HPV-16 capsid; HPV16 capsid protein; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16; major capsid protein L1; L1; Major capsid L1 protein; Major capsid protein; Major capsid protein L1; HPV16
Related Product

For lab research use only, not for diagnostics, therapeutic or any in vivo human use.

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