APP

APP is lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. unctions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3798 Recombinant APP Protein (Met1-Leu669) [His] Mammalian cells Recombinant APP Protein (Met1-Leu669) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 98.59 kDa. (Uniprot ID: P05067) APP Tumor Antigens Datasheet 100 µg Inquiry
VAng-3391Lsx Recombinant Human APP Protein E. coli Recombinant Human Amyloid beta A4 protein, expressed in E. coli. (Uniprot ID: P05067) APP Tumor Antigens Datasheet 100 µg Inquiry
VAng-3392Lsx Recombinant Human APP Protein (aa 18-770) Cell Free Expression Recombinant Human Amyloid beta A4 protein, expressed in cell free expression systems. (Uniprot ID: P05067) APP Tumor Antigens Datasheet 10 µg Inquiry
VAng-3393Lsx Recombinant Human APP Protein (aa 18-289) [His] E. coli Recombinant Human Amyloid beta A4 protein, expressed in E. coli. (Uniprot ID: P05067) APP Tumor Antigens Datasheet 100 µg Inquiry
VAng-3394Lsx Recombinant Human APP Protein (AA 672-709) [His] [GST] E. coli Recombinant Human Amyloid beta A4 protein, expressed in E. coli. (Uniprot ID: P05067) APP Tumor Antigens Datasheet 20 µg Inquiry

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