CD44

CD44 is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. The standard isoform, designated CD44s, comprising exons 1–5 and 16–20 is expressed in most cell types. CD44 splice variants containing variable exons are designated CD44v. Some epithelial cells also express a larger isoform (CD44E), which includes exons v8–10. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3929 Recombinant Mouse CD44 Protein (aa 1-224) [His] Mouse Recombinant Mouse CD44 Protein (Met1-Thr224) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 23.6 kDa. (Accession ID: NP_001034240.1) CD44 Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr3930 Recombinant Human CD44 Protein (aa 1-220) [His] Human Recombinant Human CD44 Protein (Met 1-Pro 220) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 23.4 kDa. (Accession ID: P16070-1) CD44 Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr3931 Recombinant Human CD44 Protein (aa 1-220) [Fc] Human Recombinant Human CD44 Protein (Met 1-Pro 220) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.1 kDa. (Accession ID: P16070-1) CD44 Tumor Antigens Datasheet 100 µg Inquiry
VAng-1320Lsx Recombinant CD44 Protein (Gln 21-Pro 220) [Fc] HEK293 Cells. Human CD44, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH04372) CD44 Tumor Antigens Datasheet 100 µg Inquiry
VAng-1321Lsx Recombinant CD44 Protein (Gln 21-Pro 220) [His] HEK293 Cells. Human CD44, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH04372) CD44 Tumor Antigens Datasheet 100 µg Inquiry

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