GITR

GITR is a protein that in humans is encoded by GITR gene. GITR is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3841 Recombinant GITR Protein (Met1-Glu161) [His] Mammalian cells Recombinant GITR Protein (Met1-Glu161) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 25 kDa. (Uniprot ID: Q9Y5U5) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1685Lsx Human GITR Protein (Gln 26-Glu 161) [Fc] [Avi] HEK293 Cells. Biotinylated Human GITR (TNFRSF18), Fc tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1) GITR Tumor Antigens Datasheet 25 µg Inquiry
VAng-1686Lsx Human GITR Protein (Gln 26-Glu 161) [His] HEK293 Cells. Human GITR (TNFRSF18), His Tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1687Lsx Human GITR Protein (Gln 26-Glu 161) [His] [Avi] HEK293 Cells. Biotinylated Human GITR (TNFRSF18), His tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1) GITR Tumor Antigens Datasheet 25 µg Inquiry
VAng-1688Lsx Human GITR Protein (Gln 26-Glu 161) [human IgG1 Fc Tag] HEK293 Cells. Human GITR (TNFRSF18), human IgG1 Fc Tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1689Lsx Human GITR Protein (Gln 26-Glu 161) [mouse IgG2a Fc Tag] HEK293 Cells. Human GITR (TNFRSF18), Mouse IgG2a Fc Tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1690Lsx Human GITR Protein (Gly 23-Pro 154) [His] HEK293 Cells. Human GITR (TNFRSF18), His tag, is expressed in human 293 cells. (Uniprot ID: D7F619-1) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1918Lsx Mouse GITR Protein (Ser 22-His 153) [Fc] HEK293 Cells. Mouse GITR (TNFRSF18), Fc Tag, is expressed in human 293 cells. (Uniprot ID: Q8C4K3) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1919Lsx Mouse GITR Protein (Ser 22-His 153) [His] HEK293 Cells. Mouse GITR (TNFRSF18), His Tag, is expressed in human 293 cells. (Uniprot ID: Q8C4K3) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1950Lsx Rat GITR Protein (Gln 20-Lys 121) [Fc] HEK293 Cells. Rat GITR (TNFRSF18), Fc Tag, is expressed in human 293 cells. (Uniprot ID: Q5M835) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-1951Lsx Rat GITR Protein (Gln 20-Lys 121) [His] HEK293 Cells. Rat GITR (TNFRSF18), His Tag, is expressed in human 293 cells. (Uniprot ID: Q5M835) GITR Tumor Antigens Datasheet 100 µg Inquiry
VAng-2529Lsx Rhesus macaque GITR Protein (Gln 26-Glu 161) [Fc] HEK293 Cells. Rhesus macaque GITR (TNFRSF18), Fc Tag, is expressed in human 293 cells. (Uniprot ID: F7DDV8) GITR Tumor Antigens Datasheet 100 µg Inquiry

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