c-di-GMP Sodium Salt (VAdv-Ly0023)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0023 |
|
c-di-GMP sodium salt, a STING agonist vaccine adjuvant.
Datasheet
Specifications
Type
PRRs Agonist
Formula
C20H22N10O14P2▪2Na
Molecular Weight
734.38
Specificity
Th1/Th2 response
Product Form
White solid
Percentage
≥ 95% by LC/MS
Endotoxin
Lower than 5 EU/mg.
Storage
Store at -20°C.
Shelf Life
1 year.
Adjuvant Information
Introduction
c-di-GMP is an intracellular signaling molecule produced by bacteria. Administration of c-di-GMP can induce a strong immune response in vitro and in vivo. It was recently found that this cyclic dinucleotide induces the production of cytokines, such as type I interferons, through the STING/TBK1/IRF3 pathway. This adjuvant acts through the recruitment of monocytes and granulocytes, and the maturation of dendritic cellsis a cyclic dinucleotide (CDN) produced by bacteria in which it acts as a prevalent intracellular messenger.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
