Recombinant CD86 Protein (Met1-Pro247) [His] (VAng-Cr3851)
Recombinant CD86 Protein (Met1-Pro247) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 47 kDa. (Uniprot ID: P42081)
Datasheet
Specifications
Source
Mammalian cells
Target
CD86
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
CD86 is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Alternative Names
CD28LG2
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
