Monophosphoryl Lipid A (Synthetic) (VAdv-Ly0012)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0012 |
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Synthetic Monophosphoryl Lipid A, pure compound, a TLR4-based vaccine adjuvant.
Datasheet
Specifications
Type
Lipopolysaccharide
Formula
C96H184N3O22P
Product Form
White powder
Storage
Store at -20°C.
Adjuvant Information
Introduction
Synthetic Monophosphoryl Lipid A from E. coli (MPLA) is a pure compound produced by chemical synthesis that displays greatly reduced toxicity while maintaining most of the immunostimulatory activity of lipopolysaccharide. MPLA contains 6 fatty acyl groups, while MPLA purified from bacteria contains a mixture of 5, 6,and 7 acyl lipid A. MPLA is a potent stimulator of T cell and antibody responses. MPLA activates TLR4 but does not activate TLR2 reflecting its high purity. It has been used extensively in clinical trials as a component in prophylactic and therapeutic vaccines targeting infectious disease, cancer and allergies.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
