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GlycoErase™ UGP2 Knockout HEK293 Cell Line

CAT#: GLJF-0825-JF488

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ UGP2 knockout HEK293 cell line is a HEK293 model with UGP2 removed. UGP2 encodes UDP-glucose pyrophosphorylase, generating UDP-glucose, a central metabolite for glycogen synthesis and glycosylation. The knockout provides a human context to study nucleotide-sugar metabolism, glycogen assembly, and glycosylation control, supporting applications in metabolic disease research, glycoengineering, and biomanufacturing.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
UGP2
Full Name
Udp-Glucose Pyrophosphorylase 2
Alternative Name
UDPG; UGP1; DEE83; UDPGP; UGPP1; UGPP2; EIEE83; SVUGP2; UDPGP2; pHC379
Location
2p15
Gene ID
7360
Summary
The encoded enzyme transfers glucose from glucose-1-phosphate to MgUTP, producing UDP-glucose and MgPPi. UDP-glucose is a glycogen precursor in liver and muscle and a lactose precursor in lactating mammary tissue. Eukaryotic and prokaryotic forms are structurally distinct. Two isoforms arise from alternative splicing.
For Research Use Only.
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