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50 mg | ||
100mg |
Product Description | L-Lysine-2HCl for SILAC is a form of the essential amino acid L-lysine specifically prepared for use in stable isotope labeling by amino acids in cell culture (SILAC). While it's the standard, unlabeled form of lysine, it serves as the counterpart to its stable isotope-labeled versions (like 13C6-lysine). In SILAC experiments, researchers often use both labeled and unlabeled lysine in separate cell populations to establish a baseline for comparison. The unlabeled L-lysine-2HCl helps define the "light" proteome, against which the "heavy" (labeled) proteome is compared in mass spectrometry analysis. This comparison allows for precise quantification of relative protein abundance changes between different experimental conditions. |
CAS | 657-26-1 |
Synonyms | 657-26-1; MFCD00066389; L-Lysine-2HCl; L-Lysine dihydrochloride; Lysine dihydrochloride; (S)-2,6-Diaminohexanoic acid dihydrochloride; L-(+)-Lysine dihydrochloride |
Formula | C6H16C12N2O2 |
MDL No. | MFCD00066389 |
MW | 219.11 |
InChI | InChI=1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m0../s1 |
InChI Key | JBBURJFZIMRPCZ-XRIGFGBMSA-N |
Purity | Min. 95% |
Identity | Conforms to structure |
Storage | Store at 2-8°C for long term storage. |
Application | The use of L-Lysine-2HCl for SILAC facilitates accurate, reproducible, and high-throughput analysis of complex protein mixtures, advancing research in fields such as cell biology, molecular biology, and biomedical sciences. |