Biotin sphingosine

This is an N-biotinyl-labeled sphingosine, a lipid molecule used primarily as a research probe due to the biotin tag. Sphingosine itself is an alkylated sphingoid base synthesized with the natural (2S, 3R, 4E) stereochemistry. Biotin tagging allows for the tracking and quantification of sphingosine in cellular studies, as it is a potent inhibitor of protein kinase C (PKC) activity at micromolar concentrations.

752987-57-8

5-[(3aS,4S,6aR)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[(E,16R,17S)-17-amino-16,18-dihydroxyoctadec-14-enyl]pentanamide; Erythro-omega-amino sphingosine biotinamide; N-((16R,17S,E)-17-Amino-16,18-dihydroxyoctadec-14-en-1-yl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Omega-biotinyl D-erythro-sphingosine

C₂₈H₅₂N₄O₄S

540.8

InChI=1S/C28H52N4O4S/c29-22(20-33)24(34)16-12-10-8-6-4-2-1-3-5-7-9-11-15-19-30-26(35)18-14-13-17-25-27-23(21-37-25)31-28(36)32-27/h12,16,22-25,27,33-34H,1-11,13-15,17-21,29H2,(H,30,35)(H2,31,32,36)/b16-12+/t22-,23-,24+,25-,27-/m0/s1

NYQVYZZGZCNEMF-RPRIXWAOSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.