Recombinant Human Dystroglycan 1, Wheat germ

Recombinant Human Dystroglycan 1 (AAH12740) was produced using Wheat germ cell-free expression system. Measured by its binding ability in a functional ELISA.

Measured by its binding ability in a functional ELISA.

Wheat germ cell-free expression system

Human

>90%, determined by SDS-PAGE.

Unconjugated

DAG1

Dystroglycan 1

This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

Dystroglycan 1; Dystrophin-associated glycoprotein-1; Dystrophin-associated glycoprotein 1; Alpha-Dystroglycan; Beta-Dystroglycan; MDDGC7; 156DAG; MDDGC9; AGRNR; A3A; DAG