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Recombinant human ADAMTS10 protein (NP_001269281.1) is produced in Fuco-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degree.
Source
Fuco-Adjusted Human Cell Lines
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
ADAMTS10
Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 10
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.