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Recombinant Human APELA Protein, Glycoengineered Pichia pastoris

CAT#: GLJF-0622-JF58

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant human APELA protein (NP_001284479.1) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Source
Glycoengineered Pichia pastoris
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
APELA
Full Name
Apelin receptor early endogenous ligand
Gene ID
100506013
Uniprot ID
P0DMC3
Accession Number
NP_001284479.1
Background
This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone.
Alternate Names
Protein Elabela; ELA; Protein Toddler; APELA; ELA; TDL
For Research Use Only.
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