mPEG-DSPE (2000)

mPEG-DSPE (2000) is a synthetically modified phosphatidylethanolamine featuring a polyethylene glycol (PEG) chain. This molecule is a key material in nanomedicine, primarily used to stabilize liposomes and lipid nanoparticles (LNPs). The large, hydrophilic PEG headgroup creates a protective hydration shell around the particle, which effectively reduces clearance by the reticuloendothelial system and significantly extends the circulation time in the bloodstream, enabling passive drug targeting.

474922-77-5

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-polyethyleneglycol; 18:0 PEG PE; 18:0 PEG2000 PE; Azane;[3-[hydroxy-[2-(2-methoxyethoxycarbonylamino)ethoxy]phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate

C₄₅H₉₁N₂O₁₁P

867.2

InChI=1S/C45H88NO11P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-43(47)54-40-42(41-56-58(50,51)55-37-36-46-45(49)53-39-38-52-3)57-44(48)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h42H,4-41H2,1-3H3,(H,46,49)(H,50,51);1H3

KBXRORNJMUHWKT-UHFFFAOYSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.