4A3-SC8

4A3-SC8 is an advanced ionizable lipid dendrimer component engineered for the synthesis of lipid nanoparticles (LNPs) used in nucleic acid (RNA) delivery systems. By integrating additional lipids with varying charges, such as DOTAP or PA, into the 4A3-SC8 LNP structure, the system gains the capacity for targeted RNA delivery to distinct anatomical sites, specifically the liver, lungs, and spleen.

1857340-78-3

2-[3-[3-[3-[Bis[3-[2-(2-methyl-3-octylsulfanylpropanoyl)oxyethoxy]-3-oxopropyl]amino]propyl-methylamino]propyl-[3-[2-(2-methyl-3-octylsulfanylpropanoyl)oxyethoxy]-3-oxopropyl]amino]propanoyloxy]ethyl 2-methyl-3-octylsulfanylpropanoate; SCHEMBL18811301; HY-148559

C₇₅H₁₃₉N₃O₁₆S₄

1467.18

InChI=1S/C75H139N3O16S4/c1-10-14-18-22-26-30-56-95-60-64(5)72(83)91-52-48-87-68(79)36-44-77(45-37-69(80)88-49-53-92-73(84)65(6)61-96-57-31-27-23-19-15-11-2)42-34-40-76(9)41-35-43-78(46-38-70(81)89-50-54-93-74(85)66(7)62-97-58-32-28-24-20-16-12-3)47-39-71(82)90-51-55-94-75(86)67(8)63-98-59-33-29-25-21-17-13-4/h64-67H,10-63H2,1-9H3

HMIDEMNFLBUNTB-UHFFFAOYSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.