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GlycoErase™ PGM5 Knockout HEK293 Cell Line

CAT#: GLJF-0825-JF434

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PGM5 knockout HEK293 cell line is a HEK293 model with PGM5 expression eliminated. PGM5 encodes a phosphoglucomutase implicated in carbohydrate processing, glycogen metabolism, and galactose utilization. In humans, it is also enriched in muscle-associated structures. The knockout model enables exploration of energy balance, muscle-linked glycogen processing, and human carbohydrate regulation in a kidney-derived cellular system.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PGM5
Full Name
Phosphoglucomutase 5
Alternative Name
PGMRP
Location
9q21.11
Gene ID
5239
Summary
Phosphoglucomutases like PGM5 are crucial in converting glucose-1-phosphate to glucose-6-phosphate, playing a key role in glycogen formation and glucose metabolism.
For Research Use Only.
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