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| Size | Qty | Add To Basket |
|---|---|---|
| 1×48 T | ||
| 1×96 T |
| Product Description | The quantitative human GRIA1 (glycosylated) sandwich ELISA kit is designed to detect human glutamate receptor, ionotropic, AMPA1 (GRIA1) levels. GRIA1 is a subunit of the AMPA receptor. AMPA receptors are ligand-gated ion channels in the central nervous system. GRIA1 plays a crucial role in fast synaptic transmission, which is fundamental for learning, memory, and neuronal communication. The kit is suitable for various biological samples such as tissue homogenates. Its sensitivity is 0.058 ng/mL, which can accurately detect low concentrations of GRIA1 in the sample. |
| Target | GRIA1 |
| N-Glycosylation Site | 63, 249, 257, 363, 401, 406 |
| Sample Types | Tissue homogenates |
| Sample Volume | 100 μL |
| Sensitivity | 0.058 ng/mL |
| Detection Principle | Quantitative sandwich ELISA |
| Detection Range | 1 ng/mL-10 ng/mL |
| Detection Time | 1 h-5 h |
| Detection Wavelength | 450 nm |
| Storage | Store at 2-8°C for long term storage. |
| Species | Human |
| Full Name | Glutamate receptor, ionotropic, AMPA1 |
| Alternate Names | GRIA1; Glutamate receptor, ionotropic, AMPA1; GLUH1; AMPA-selective glutamate receptor 1 |
| Uniprot No. | P42261 |
| Application | The quantitative human GRIA1 (glycosylated) sandwich ELISA kit is used to measure glycosylated GRIA1 levels in samples. This measurement is valuable in neuroscience research, particularly in studies of synaptic functions and neurological disorders. The kit is applied in investigations of conditions such as Alzheimer's disease, epilepsy, and stroke, where GRIA1 expression or functions may be altered. |
| Kit Components | Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution |
| Precision | Intra-Assay: n=20, CV <8%; Inter-Assay: n=20, CV <10%; |
| Recovery | Serum sample: n=5, 90-105%; Plasma sample: n=4, 85-100%; |
| Standard Curve | ![]() The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested. |