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GlycoErase™ PRKAA2 Knockout HEK293T Cell Line

CAT#: GLJF-0825-JF587

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PRKAA2 knockout HEK293T cell line removes PRKAA2, the AMPK α2 catalytic subunit involved in glucose and lipid metabolism, ACC and HMGCR regulation, insulin sensitivity, and myocardial energy balance. This knockout enables studies of glucose regulation, lipid biosynthesis, and cardiometabolic signaling.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293T
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PRKAA2
Full Name
Protein Kinase Amp-Activated Catalytic Subunit Alpha 2
Alternative Name
AMPK; AMPK2; PRKAA; AMPKa2
Location
1p32.2
Gene ID
5563
Summary
This alpha catalytic subunit of AMPK regulates cellular metabolism by phosphorylating and inactivating key enzymes such as acetyl-CoA carboxylase and HMG-CoA reductase. It is important for maintaining insulin sensitivity and heart muscle energy balance.
For Research Use Only.
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