Recombinant Human ATP binding cassette subfamily B member 1 (ABCB1), Yeast

Recombinant Human ATP binding cassette subfamily B member 1 (NP_000918.2) was expressed in Yeast with a His-tag at the N-terminus or Tag-free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.

Yeast

Human

His-tag at the N-terminus or Tag-free

>90%, determined by SDS-PAGE.

Unconjugated

ABCB1

ATP binding cassette subfamily B member 1

The protein is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs.

CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; p-170