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Recombinant Human COL18A1 protein (NP_085059.2) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors.