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Recombinant Human CRTAP protein (NP_006362.1) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
Alternate Names
Cartilage Associated Protein; Prolyl 3-Hydroxylase Family Member 5 (Non-Enzymatic); Leprecan-Like 3; CASP; LEPREL3; P3H5; OI7