GlycoErase™ PPP1R9A Knockout Jurkat Cell Line

GlycoErase™ PPP1R9A knockout Jurkat cell line is a Jurkat model with PPP1R9A deleted. PPP1R9A (neurabin-1) is an imprinted, PDZ/SAM-domain scaffold that regulates PP1 and reorganizes the actin cytoskeleton in developmental contexts. The knockout supports studies of actin dynamics, cell adhesion, and imprinting-related regulation, with applications in development and cytoskeletal signaling.

KO Cell Lines

Human

Suspension-growing

1:3~1:5

Jurkat cell line

T-cell acute lymphoblastic leukemia (T-ALL)

T Lymphocyte

T-cell acute lymphoblastic leukemia (T-ALL)

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

FBS & Penicillin/Streptomycin & RPMI

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

PPP1R9A

Protein Phosphatase 1 Regulatory Subunit 9A

NRB1; NRBI; Neurabin-I

7q21.3

This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.