0
Inquiry Basket

There is no product in the shopping cart, buy it!

GlycoFlux™ MMLV-Human SIGLEC2 Viral Particle (CAT#: GLJF-1025-JF361)

Datasheet

SPECIFIC INQUIRY
Antibiotic Resistance:
Fluorescent Reporters:
Titer:
Size:
Add to basket
Description GlycoFlux™ MMLV-SIGLEC2 Viral Particle encodes SIGLEC2 (CD22), a B-cell inhibitory receptor regulating BCR signaling and endocytosis; this MMLV platform enables stable expression in mammalian cells to interrogate B-cell checkpoints, trafficking, and therapeutic targeting mechanisms.
Product Type Recombinant MMLV Retrovirus
Target SIGLEC2
Species Human
Promotor MMLV 5' LTR promoter
Packaging System Retrovirus
Packaging Cell HEK293T
Application This MMLV vector is a common retroviral vector system that permanently integrates a gene into the host cell's genome, allowing for long-term, sustained expression. It is a popular tool for gene manipulation in dividing cells and for generating iPS cells in biomedical research.
Shipping Shipped on dry ice with temperature held at or below -80°C.
Storage Store at -80°C to maintain their titer and stability.
Handling Notes Store products at -80°C, and avoid repeated freeze-thaw cycles to maintain viral titer. For safety, always handle the products in a biological safety cabinet, using appropriate personal protective equipment like lab coats, gloves, and eye protection.
Product Disclaimer These products are for research use only and not for diagnostic or clinical use. The user assumes full responsibility for all safety protocols and compliance with relevant regulations. While we are committed to quality, Creative Biolabs makes no guarantee as to the performance of these products in a specific application.
Titer Assay qPCR
Mycoplasma Test Negative
Sterility Sterility testing confirmed no microbial contamination.
Transduction Evaluation On request, Creative Biolabs conducts in vitro or in vivo transduction assays to evaluate lentiviral delivery to target cells and to quantify transgene expression and function.
Insert Identity Confirmation Creative Biolabs verifies all retroviral vectors by a PCR-based proviral integration check. In brief, cells are transduced with serial dilutions of the retroviral preparation and, after several days, genomic DNA is extracted. A predefined segment of the expected retroviral insert is then amplified by PCR to confirm correct identity and integration.
Full Name Sialic Acid Binding Ig Like Lectin 2
Alternative Name SIGLEC-2; CD22; Sialic Acid Binding Ig Like Lectin
Location 19q13.12
Gene ID 8778
Summary The protein is predicted to have activities such as binding to CD4 receptors, protein phosphatases, and sialic acid. It plays a role in activating B cells, negatively regulating the B cell receptor signaling pathway, and controlling endocytosis. The protein is localized in early and recycling endosomes and has been implicated in the development of diffuse large B-cell lymphoma.
For Research Use Only.
Online Inquiry
Creative Biolabs-Glycoprotein Follow us on
  • ()
    ()
    ()
ISO 9001 Certified - Creative Biolabs Quality Management System.