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Quantitative Human AMR (Glycosylated) Sandwich ELISA Kit (CAT#: GLJF-0525-HX36)

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1×48 T
1×96 T

Product Description The quantitative human AMR (glycosylated) sandwich ELISA kit is designed to detect human adrenomedullin receptor (AMR) levels. AMR, also known as calcitonin receptor-like receptor (CALCRL) in complex with RAMP2 or RAMP3, is a G protein-coupled receptor that mediates the effects of adrenomedullin, a peptide involved in vasodilation, angiogenesis, and cell proliferation. It plays a crucial role in cardiovascular and renal function. The kit is suitable for various biological samples such as tissue homogenates, cell lysates. Its sensitivity is 0.125 ng/mL, which can accurately detect low concentrations of AMR in the sample.
Target AMR
N-Glycosylation Site 28, 37
Sample Types Tissue homogenates, cell lysates
Sample Volume 100 μL
Sensitivity 0.125 ng/mL
Detection Principle Quantitative sandwich ELISA
Detection Range 1 ng/mL-10 ng/mL
Detection Time 1 h-5 h
Detection Wavelength 450 nm
Storage Store at 2-8°C for long term storage.
Species Human
Full Name Adrenomedullin receptor
Alternate Names AMR; Adrenomedullin receptor; ADMR; GPR182; G protein-coupled receptor 182
Uniprot No. O15218
Application The quantitative human AMR (glycosylated) sandwich ELISA kit is valuable for researchers investigating cardiovascular diseases, sepsis, and cancer, where adrenomedullin signaling is implicated. By quantifying AMR, researchers can gain insights into its role in disease pathogenesis and explore potential therapeutic targets related to vasodilation and angiogenesis.
Kit Components Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Precision Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery Serum sample: n=5, 90-105%;
Plasma sample: n=4, 80-100%;
Standard Curve
The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
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