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Quantitative Human CACNα1C (Glycosylated) Sandwich ELISA Kit

CAT#: GLJF-0525-HX580

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Specifications
Product Description
The quantitative human CACNα1C (glycosylated) sandwich ELISA kit is designed to detect human calcium channel, L-type, α1c subunit (CACNα1C) levels. CACNα1C is a protein that forms a pore-forming subunit of L-type calcium channels. These channels are found in various cell types, including heart muscle, smooth muscle, and neurons. CACNα1C plays a crucial role in processes such as muscle contraction, hormone secretion, and gene expression by controlling the flow of calcium ions across cell membranes. The kit is suitable for various biological samples such as tissue homogenates. Its sensitivity is 0.125 ng/mL, which can accurately detect low concentrations of CACNα1C in the sample.
Target
CACNα1C
Kit Components
Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Sample Types
Tissue homogenates
Sample Volume
100 μL
Sensitivity
0.125 ng/mL
Detection Principle
Quantitative sandwich ELISA
Detection Range
0.55 ng/mL-15 ng/mL
Detection Time
1 h-5 h
Detection Wavelength
450 nm
Storage
Store at 2-8°C for long term storage.
Target Information
Species
Human
Full Name
Calcium channel, L-type, α1c subunit
Alternate Names
CACNα1C; Calcium channel, L-type, α1c subunit; CACN2; CACNL1A1
Uniprot No.
N-Glycosylation Site
153, 328, 1436, 1487
Application Notes
Application
The quantitative human CACNα1C (glycosylated) sandwich ELISA kit is a valuable tool for research in cell biology and physiology, especially in studies of calcium signaling and its role in various diseases. Researchers use it to measure CACNα1C levels in different experimental systems. The kit has applications in studies of cardiovascular disease, neurological disorders, and endocrine functions.
Precision
Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;
Recovery
Serum sample: n=5, 80-100%;
Plasma sample: n=4, 95-110%;
Standard Curve

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.
For Research Use Only.
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