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| Size | Qty | Add To Basket |
|---|---|---|
| 1 mg | ||
| 500 μg |
| Product Overview | Recombinant human A2M protein (NP_000005.2) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications. |
| Source | Glycoengineered Pichia pastoris |
| Species | Human |
| Tag | His-tag, FC-tag |
| Purity | >90%, determined by SDS-PAGE. |
| Endotoxin Level | Regular batch |
| Conjugation | None |
| Target | A2M |
| Full Name | Alpha-2-macroglobulin |
| Gene ID | 2 |
| Uniprot ID | P01023 |
| Accession Number | NP_000005.2 |
| Background | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. |
| Alternate Names | Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2M; CPAMD5; FWP007 |