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Recombinant Human DAND5 protein (NP_689867.1) is produced in Fuco-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degree.
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.