GlycoErase™ HEK293T XYLT2 Knockout Cell Line

We are pleased to present an XYLT2 knockout HEK293T cell line, designed to facilitate research on glycosaminoglycan biosynthesis. This cell line, lacking the XYLT2-encoded xylosyltransferase 2, offers a valuable tool for researchers to investigate the specific roles of XYLT2 in glycosaminoglycan biosynthesis and its impact on cellular functions. Utilizing HEK293T cells, a platform well-suited for gene function and regulation studies, researchers can gain a deeper understanding of the role of XYLT2 in maintaining protein homeostasis.

KO Cell Lines

Human

Epithelial-like, adherent

1:2~1:4

HEK293T

Embryonic kidney

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

DMEM & FBS & Penicillin/Streptomycin

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

XYLT2

Xylosyltransferase 2

PXYLT2, XT-II

17q21.33

Xylosyltransferase that initiates glycosaminoglycan chain biosynthesis; enzyme activity is increased in scleroderma patients and serves as a diagnostic marker.